Premature ejaculation (PE) is a frustrating condition where men aren’t able to control how long they can have sex before ejaculating. For some men, it can be embarrassing, even causing mental anguish, anxiety and depression. Many men who suffer from PE might be desperate to find help or a cure, and they may be willing try almost anything, including pills, to help premature ejaculation. While there are a number of products out there that claim to help PE, we live in a society where popping a pill to find a cure seems to have become the norm. It’s easy, it’s quick and there are high hopes it will work. But beware, even though there are pills out there claiming to cure or reduce PE, this form of treatment does not come without its own set of caveats. We dive deeper into the types of premature ejaculation pills below.

Key Takeaways

There are two types of premature ejaculation pills available for men. Also called stamina pills, there are both herbal and pharmaceutical options in a pill form. None of the herbal pills have been scientifically proven to help PE. And the pharmaceutical versions are ultimately antidepressants in the form of SSRIs, which have been shown to be effective at delaying ejaculation in numerous clinical studies. However, as promising as that may sound, it’s very important to understand and keep in mind, these prescription-only options have potential side effects that can be even worse than the problem they’re trying to fix.

Herbal Pills for Premature Ejaculation

In an analysis of herbal premature ejaculation pills on the market, two things stand out:

  1. Each brand has a different combination of ingredients.
  2. Each brand makes claims of far-reaching capabilities, while often providing warnings that alternative products are useless compared to theirs.

These PE pills are typically labeled as being a solution for sexual stamina, a term that can mean very different things to different people. Be most careful of Chinese herbal medication.

Herbal medicines have been around for thousands of years. Logically, it would make sense that if an herb or combination of herbs was truly effective in allowing men to have longer-lasting sex, this would be one of the most popular herbs known to mankind. The fact that there is very little overlap in key ingredients in the commonly advertised herbal sexual enhancement pills leads you to believe it's more probable that, really, none of these pills actually work. If such an herb existed, wouldn't it be included in every product? Let's take a closer look at two ingredients that are common in more than one product.


L-arginine is an amino acid found in meat, fish and poultry. In the body, L-arginine is converted to nitric oxide, a molecule that’s used to control blood flow. PDE-5 inhibitors indirectly elevate nitric oxide in order to increase blood flow to the penis to treat erectile dysfunction (ED). But while some studies have shown ED improvement in men taking L-arginine, no such positive results for premature ejaculation have been found.

L-arginine is also a common ingredient in many penile enhancement pills. Recently, hundreds of these performance enhancement pill manufacturers were banned by the FDA for illegally tainting their so-called "natural" supplements with sildenafil or other PDE-5 inhibitors in order to deliver better results. In fact, this practice is so common, we can probably conclude that L-arginine likely doesn’t have much, if any, efficacy as an FDA Approved erectile dysfunction medication. We should also point out here the warranted concern of another pretty clear misleading practice – male sexual enhancement supplement manufacturers claim improvement in nearly every aspect of male sexual performance: ED, PE, libido and yes, even penis size.

St. John’s Wort

St. John’s Wort is an herb used in many herbal supplements. It’s said to treat a variety ailments including: depression, somatic symptom disorders, alcoholism, wounds, burns, muscle pain, ADHD, Parkinson's disease, premenstrual syndrome (PMS) and irritable bowel syndrome (IBS). St. John’s Wort is found in some herbal products claiming to be effective in treating PE. But given that St. John's Wort has been medicinally used since the time of ancient Greece, wouldn’t you agree that if it were effective in treating PE, this would have surely been discovered long ago? We could say the same thing for a long list of other herbs used in herbal treatments claiming to help men with PE.


Most of the herbal premature ejaculation pill products on the market today make bold statements about performance and effectiveness, and not just for PE. It’s more than just a little unnerving to think about the wild claims being made with little to no regard for the actual safety of an herbal supplement. Inadequate testing and limited regulations on how companies market these products should be concerning to us all. For each product listed below, we searched the internet for clinical studies to back up performance claims.

  • Prosolutions Plus™ - “64% improvement in premature ejaculation” - Their clinical study doesn’t mention the product name and, furthermore, has no mention of IELT or time of sex at all. It’s also interesting that the Prosolutions Plus claim of 64% is exactly the same as Promescent’s clinical data. If the product producer performs a clinical study, we invite them to provide us this information and we will gladly update this web page.
  • Ejacutrol – "Simply take Ejacutrol before sex and last three, five or even ten times longer." "Ejacutrol is the most advanced and effective product on the market." – No clinical data is provided to back up these extraordinary claims.
  • PrematureX – “addresses the root cause of premature ejaculation that originates from either the mental aspect (nervousness, anxiety) or the physical aspect (oversensitivity).” - We couldn’t find any clinical data to back up these amazing claims that this PE Pill works simultaneously on the brain and the penis.
  • DelayMaxx – "Last 4 - 5 Times Longer On Bed!" - We cannot find clinical data. Promescent is a leading PE solution in the USA with 64% improvement in IELT. You would think that a PE product that enables men to last 4-5 times longer would be annihilate every other product on the market.
  • RizerXL – "Generate rock-hard erections. Stop premature ejaculation. Increase stamina and endurance. Increase ejaculate amount. Treat erectile dysfunction. Increase your libido." – Clinical data to back up these grandiose claims doesn’t appear to exist.
  • Duramale – "Permanent Results" – We find it interesting that they suggest purchasing a year’s supply.
Pills for Premature Ejaculation

Pharmaceutical Pills for Premature Ejaculation

But not all pills prescribed for PE are herbal. There are two pharmaceutical technologies that have clinical data indicating effectiveness for premature ejaculation. Tramadol, which is indicated to treat pain, is prescribed off-label to treat PE. Yet in spite of some clinical success, Tramadol is falling out of favor, as new topical treatments with low side effect profiles continue to emerge in the market. It seems a lot of men prefer topical sprays and gels over a pill.


Tramadol is a strong synthetic opioid analgesic. While it isn’t entirely clear how it works to delay ejaculation, it’s generally accepted that a combination of effects is coming into play. In short, Tramadol may be acting as a selective serotonin reuptake inhibitor (SSRI), similar to dapoxetine, numbing the entire nervous system to stimuli. While it was once thought to be effective in treating PE, the numerous side effects and potential for addiction have since changed the course of treatment by many specialists in sexual medicine.


Dapoxetine, also known as Priligy, is another SSRI that works to delay ejaculation. It is the only prescription drug specifically manufactured to treat PE, taken on an as-needed basis. When taken about three hours before sexual activity, studies have shown that dapoxetine can increase the intra-vaginal ejaculation latency time (IELT), which is the time it takes from vaginal penetration to male orgasm.

Pros and Cons of Using Pills to Delay Ejaculation

As with most things medically concerned, there are both pros and cons to taking pills to treat PE. One of the biggest pros may simply be the feeling of control a man has when he can take something to last longer and enjoy sex on a regular basis. There are also some cons to using a pill for treatment. You may need to go through the hassle of getting a prescription (if you’re considering something that’s not available over-the-counter), and herbal remedies in the pill form can be questionable in terms of safety and efficacy. Before you look for the best premature ejaculation pills on the market, keep the following pros and cons in mind.


  • Herbal pills are easy to get without a prescription.
  • Can be reasonably priced.
  • Easy to take.
  • Less mess than applying a spray, gel or cream that needs to be rubbed in.
  • No potential for any transference to a partner.


  • Potential cost can be exorbitant.
  • Need to plan sex – some pills need to be taken up to three hours prior to intercourse.
  • There is limited evidence and research on herbal pills.
  • There can be side effects to prescription pills, including potential addiction, loss of libido and erectile dysfunction
  • There may be unknown side effects of some herbal alternatives.
  • Some herbal alternatives have FDA safety warnings
  • Inconsistent “cures” in herbal remedies – few products have like ingredients, which raises the question: how effective can an herb be if only one product is using it?? Wouldn’t they all be using this wonder-cure?
  • Questionable advertising of herbal options – big claims with not much to support them.

Where to Buy

Walmart, Walgreens and GNC are the stores with the largest variety of over the counter (OTC) premature ejaculation pills.

You should not take any type of delay pills with consulting a doctor.

See your doctor prior to considering any of these treatments.

Buy Promescent Now