BPC 157 for Erectile Dysfunction

Erectile dysfunction is a common problem among men. Find out how BPC-157 may potentially be an effective treatment for erectile dysfunction.

The Promescent Team
Hands on, practical experience – this is our expertise
by The Promescent Team Last updated 12/11/2023
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Erectile dysfunction is a common problem among men. It affects about 50% of males over the age of 40.

There are a variety of treatments that have been used to treat ED. One new possibility that’s been explored is BPC-157.

Quick FAQs

BPC-157 is a peptide that consists of 15 amino acids derived from a naturally occurring protein in the human gastric juice.

While it has not been studied as a treatment for ED, BPC-157 promotes angiogenesis and nerve regeneration, which may help improve erectile function.

BPC-157 is generally thought to be safe, but some side effects that may occur include dizziness, headaches, and changes in appetite.

Recent research has shown there may be a promising relationship between BPC-157 and erectile dysfunction.

It’s important to know the science behind BPC-157, its potential in treating erectile dysfunction, as well as dosage, safety, and side effects.

What is BPC-157?

BPC-157, or Body Protective Compound 157, is a synthetic peptide consisting of 15 amino acids. It is derived from a naturally occurring protein found in human gastric juice. 

BPC-157 has gained significant attention due to its potential benefits in tissue repair, inflammation reduction, and pain relief. It is also known for supporting gut health.

The synthetic peptide was synthesized starting in the 1990s. It’s yet to be approved by the FDA for medical use, and there’s been little data on its effects on humans. It has also been banned by the US Anti-Doping Agency and the World Anti-Doping Agency.

Erectile Dysfunction: Causes and Symptoms

Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It affects millions of men worldwide and can result from various factors, including:

  • Psychological factors such as stress, anxiety, and depression
  • Vascular issues that limit blood flow to the penis
  • Neurological problems affecting nerve signals
  • Hormonal imbalances, such as low testosterone levels
  • Lifestyle factors like smoking, alcohol consumption, and obesity

    Common symptoms of erectile dysfunction include:

    • Difficulty getting an erection
    • Difficulty maintaining an erection
    • Reduced sexual desire

    BPC-157's Role in Treating Erectile Dysfunction

    No study has been conducted testing BPC-157’s effectiveness in ED patients. Nonetheless, recent studies have demonstrated BPC-157's potential in treating erectile dysfunction by addressing some of the underlying causes. Key benefits include:

    Angiogenesis Promotion

    BPC-157 has been shown to promote angiogenesis – the formation of new blood vessels. This can improve blood flow to the penis, a crucial factor in achieving and maintaining an erection.

    Pro Tip: VitaFLUX Nitric Oxide Booster helps to relax blood vessels and allow more blood flow through increased nitric oxide production.

    Nerve Regeneration

    BPC-157 has exhibited nerve regenerative properties in animal studies. By promoting nerve repair and regeneration, it can help restore proper nerve signaling essential for erectile function.

    Anti-inflammatory and Antioxidant Effects

    Inflammation and oxidative stress can contribute to erectile dysfunction. BPC-157's anti-inflammatory and antioxidant properties can help counteract these factors, promoting overall penile health.

    BPC-157 Dosage and Administration for Erectile Dysfunction

    There is currently no standardized BPC-157 dosage specifically for erectile dysfunction. In studies of its effects on different ailments, various dosage amounts have been used.

    BPC-157 can be administered as an injection or an oral dosage.The duration of treatment varies based on individual needs and response to therapy.

    It is crucial to consult a healthcare professional before starting BPC-157 treatment for ED. They may recommend an appropriate dosage and monitor your progress throughout the therapy.

    Other benefits of BPC-157

    BPC-157 has been shown to potentially have other benefits beyond treating erectile dysfunction. Here are a few worth noting.

    • Injury recovery: Research published in the Journal of Applied Physiology found that BPC-157 can increase the speed of tendon healing. 
    • Antidepressant effect: A study found that BPC-157 was effective in reducing the immobility of chronically stressed rats.
    • Healing effect on TBI: BPC-157 was concluded to be successful in counterracting the effects of a traumatic brain injury.
    • Improved gastrointestinal health: One research study has shown BPC-157 can be effective in healing different parts of the digestive system.
    • Wound healing: Research published in Frontiers in Pharmacology concluded that BPC-157 could help with wound healing and counteracting bleeding disorders produced by amputation.
      • Reduce MPTP damage: MPTP is a toxin that induces damage that’s similar to what occurs with Parkinson’s Disease. BPC-157 was found to reduce the damage caused by MPTP.

      Safety and Side Effects of BPC-157

      BPC-157 has been shown to be safe in preclinical studies and generally has no side effects reported. However, like any therapeutic agent, individual reactions may vary. Some potential side effects include:

      • Dizziness
      • Headaches
      • Changes in appetite

      It is essential to consult a healthcare professional before using BPC-157 to discuss potential risks and ensure the treatment is suitable for your specific needs.

      Takeaways

      ED is a struggle among many men over 40. BPC-157 holds promise as a potential treatment option for erectile dysfunction, addressing key underlying factors such as angiogenesis, nerve regeneration, and inflammation.

      While research is still in its early stages, the current body of evidence suggests that BPC-157 may offer an innovative approach to improving sexual health.

      As always, it is crucial to consult a healthcare professional to determine the appropriate dosage and administration for your specific needs and to monitor your progress throughout the treatment.

      The Promescent Team

      The Promescent Team

      Our team has over a decade of experience in the sexual wellness field and are experts in sexual dysfunctions, like premature ejaculation. We help couples and individuals better understand treatment options available for different types of sexual needs and educate the public on all things related to intimacy. All of our authored content is medically reviewed for accuracy and reliability.

      Sources:

      Absorption Pharmaceuticals LLC (Promescent) has strict informational citing guidelines and relies on peer-reviewed studies, academic or research institutions, medical associations, and medical experts. We attempt to use primary sources and refrain from using tertiary references and only citing trustworthy sources. Each article is reviewed, written, and updated by Medical Professionals or authoritative Experts in a specific, related field of practice. You can find out more about how we ensure our content is accurate and current by reading our editorial policy.

      • "What Age Does Erectile Dysfunction Start? - UnityPoint Health." Unitypoint.org, 2023, www.unitypoint.org/news-and-articles/what-age-does-erectile-dysfunction-start---unitypoint-health. Accessed on May, 10, 2023.
      • Sikiric P, Skrtic A, Gojkovic S, Krezic I, Zizek H, Lovric E, Sikiric S, Knezevic M, Strbe S, Milavic M, Kokot A, Blagaic AB, Seiwerth S. Cytoprotective gastric pentadecapeptide BPC 157 resolves major vessel occlusion disturbances, ischemia-reperfusion injury following Pringle maneuver, and Budd-Chiari syndrome. World J Gastroenterol. 2022 Jan 7;28(1):23-46. doi: 10.3748/wjg.v28.i1.23. PMID: 35125818; PMCID: PMC8793015. Accessed on May, 10, 2023.
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      • Hsieh MJ, Liu HT, Wang CN, Huang HY, Lin Y, Ko YS, Wang JS, Chang VH, Pang JS. Therapeutic potential of pro-angiogenic BPC157 is associated with VEGFR2 activation and up-regulation. J Mol Med (Berl). 2017 Mar;95(3):323-333. doi: 10.1007/s00109-016-1488-y. Epub 2016 Nov 15. PMID: 27847966. Accessed on May, 10, 2023.
      • Gjurasin M, Miklic P, Zupancic B, Perovic D, Zarkovic K, Brcic L, Kolenc D, Radic B, Seiwerth S, Sikiric P. Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury. Regul Pept. 2010 Feb 25;160(1-3):33-41. doi: 10.1016/j.regpep.2009.11.005. Epub 2009 Nov 10. PMID: 19903499. Accessed on May, 10, 2023.
      • Filosevic, A., Waldowski, R.A., Vidovic, T., Sikiric, P. and Drmic, D. (2017), Stable Gastric Pentadecapeptide BPC 157 Antagonizes Hydrogen Peroxide Induced Oxidative Stress in Drosophila melanogaster. The FASEB Journal, 31: 667.14-667.14. https://doi.org/10.1096/fasebj.31.1_supplement.667.14. Accessed on May, 10, 2023.
      • Chang CH, Tsai WC, Hsu YH, Pang JH. Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts. Molecules. 2014 Nov 19;19(11):19066-77. doi: 10.3390/molecules191119066. PMID: 25415472; PMCID: PMC6271067. Accessed on May, 10, 2023.
      • "The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration - Journal of Applied Physiology. Journals.physiology.org, 2011, www.journals.physiology.org/doi/full/10.1152/japplphysiol.00945.2010. Accessed on May, 10, 2023.
      • Sikiric P, Separovic J, Buljat G, Anic T, Stancic-Rokotov D, Mikus D, Marovic A, Prkacin I, Duplancic B, Zoricic I, Aralica G, Lovric-Bencic M, Ziger T, Perovic D, Rotkvic I, Mise S, Hanzevacki M, Hahn V, Seiwerth S, Turkovic B, Grabarevic Z, Petek M, Rucman R. The antidepressant effect of an antiulcer pentadecapeptide BPC 157 in Porsolt's test and chronic unpredictable stress in rats. A comparison with antidepressants. J Physiol Paris. 2000 Mar-Apr;94(2):99-104. doi: 10.1016/s0928-4257(00)00148-0. PMID: 10791689. Accessed on May, 10, 2023.
      • Sikiric P, Seiwerth S, Rucman R, Kolenc D, Vuletic LB, Drmic D, Grgic T, Strbe S, Zukanovic G, Crvenkovic D, Madzarac G, Rukavina I, Sucic M, Baric M, Starcevic N, Krstonijevic Z, Bencic ML, Filipcic I, Rokotov DS, Vlainic J. Brain-gut Axis and Pentadecapeptide BPC 157: Theoretical and Practical Implications. Curr Neuropharmacol. 2016;14(8):857-865. doi: 10.2174/1570159x13666160502153022. PMID: 27138887; PMCID: PMC5333585. Accessed on May, 10, 2023.
      • Sikiric P, Drmic D, Sever M, Klicek R, Blagaic AB, Tvrdeic A, Kralj T, Kovac KK, Vukojevic J, Siroglavic M, Gojkovic S, Krezic I, Pavlov KH, Rasic D, Mirkovic I, Kokot A, Skrtic A, Seiwerth S. Fistulas Healing. Stable Gastric Pentadecapeptide BPC 157 Therapy. Curr Pharm Des. 2020;26(25):2991-3000. doi: 10.2174/1381612826666200424180139. PMID: 32329684. Accessed on May, 10, 2023.
      • Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, Pavlov KH, Petrovic A, Sikiric S, Vranes H, Prtoric A, Zizek H, Durasin T, Dobric I, Staresinic M, Strbe S, Knezevic M, Sola M, Kokot A, Sever M, Lovric E, Skrtic A, Blagaic AB, Sikiric P. Stable Gastric Pentadecapeptide BPC 157 and Wound Healing. Front Pharmacol. 2021 Jun 29;12:627533. doi: 10.3389/fphar.2021.627533. PMID: 34267654; PMCID: PMC8275860. Accessed on May, 10, 2023.
      • Sikiric P, Marovic A, Matoz W, Anic T, Buljat G, Mikus D, Stancic-Rokotov D, Separovic J, Seiwerth S, Grabarevic Z, Rucman R, Petek M, Ziger T, Sebecic B, Zoricic I, Turkovic B, Aralica G, Perovic D, Duplancic B, Lovric-Bencic M, Rotkvic I, Mise S, Jagic V, Hahn V. A behavioural study of the effect of pentadecapeptide BPC 157 in Parkinson's disease models in mice and gastric lesions induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydrophyridine. J Physiol Paris. 1999 Dec;93(6):505-12. doi: 10.1016/s0928-4257(99)00119-9. PMID: 10672997. Accessed on May, 10, 2023.
      • "BPC-157 - Examine." Examine.com, 2022, www.examine.com/supplements/bpc-157/. Accessed on May, 10, 2023.
      The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

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