PSD502 Tempe Spray Proves Absorption Formula

February 27, 2018

PSD502 Tempe Spray Proves Absorption Formula

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Recently, PSD502 – called TEMPE spray – has been judged safe and effective by the European Medicines Agency and is expected to be available by private prescription next year. This is good news for men who suffer from premature ejaculation across the globe.

Dr Wyllie, formerly of Pfizer and one of the inventors of Viagra, now with British biotech firm Plethora Solutions, is one of the inventors of PSD502.

PSD502 TEMPE spray had successful clinical trials in 2009, proving the effectiveness of a desensitizer with an absorption formula. PSD502 achieves its eutectic, absorbing formulation by combining lidocaine with prilocaine, similar to EMLA, a popular topical anesthetic. EMLA had been commonly prescribed in the U.S. off-label for PE but it's popularity has declined, apparently due to ineffectiveness, long wait times (30 minutes) from application to sexual activity and greasiness of the formula. EMLA is rarely prescribed today. It is believed that PSD502 has improved the absorption capability over EMLA, thus achieving faster absorption and improved ejaculatory control.

The TEMPE spray has not achieved FDA approval. Many believe that the formula contains prilocaine, which has a potentially dangerous side effect called methemoglobinemia. Promescent uses lidocaine only and is approved for use in the U.S. by way of FDA monograph 21CFR 348.10. Lidocaine is often called the "safest of the caines" by many physicians and pharmacists and has a long history of use. There's a certain comfort level that physicians have recommending products in which the only active ingredient is lidocaine.

The availability of PSD502 helps further the momentum established by Promescent that topical medications are the most effective, easy-to-use and safe method for treating premature ejaculation.

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