Deep dive on nitric oxide boosters for men and women, and testosterone boosters for sexual performance.
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Nitric oxide–boosting supplements like L-citrulline show the strongest evidence for enhancing blood flow, performance, and potentially sexual stamina; L-arginine has mixed results, especially alone; ashwagandha (part of KSM-66 blend) may raise testosterone (~10–20%) and support stress relief when used 8–12 weeks; other ingredients (zinc, magnesium, fenugreek, tribulus, etc.) offer potential but require more research. Always pair supplements with lifestyle measures and consult your healthcare provider.
Let’s be real: wanting more energy, endurance, and confidence in the bedroom is incredibly common. Whether you're experiencing occasional performance dips or simply want to feel your best, you’re not alone. Thankfully, modern nutritional science has introduced a range of supplements designed to support sexual stamina and hormone balance.
This guide dives into two categories of performance supplements: nitric oxide boosters (formulated for both men and women) and testosterone boosters (formulated for men). We’ll break down the research behind popular ingredients like L-citrulline, L-arginine, and ashwagandha so you can make informed, confident choices.
Nitric oxide (NO) is a natural molecule your body produces to help blood vessels relax and widen—a process called vasodilation. That increased blood flow plays a major role in sexual arousal and performance, especially in the pelvic region. For men, it supports firmer, longer-lasting erections. For women, it may enhance sensitivity and arousal by improving genital blood flow.
Nitric oxide levels naturally decline with age, stress, and certain health conditions. This is where nitric oxide-boosting supplements come in. They work by supplying the body with amino acids and cofactors that support NO production, especially during physical or intimate activity. The two most common are L-citrulline and L-arginine.
Let’s look at what science says about the major ingredients in many nitric oxide formulas—including those targeted at both men and women.
Citrulline is an amino acid that converts into L-arginine in the kidneys, and then into nitric oxide. Multiple studies suggest that doses of 2.4 to 6 grams per day can:
Promescent VitaFLUX nitric oxide supplements for both men and women provide 1000mg of L-Citruline per serving.
L-arginine is another amino acid involved in nitric oxide production. It’s been studied for decades, with mixed results:
The key takeaway? L-arginine may work better when paired with L-citrulline or other NO-supporting ingredients. It's also more effective in individuals who are older or have slightly impaired vascular function.
While these ingredients don’t directly boost NO, they help create a balanced internal environment for better function overall.
The male-oriented testosterone booster features a blend of vitamins, minerals, and plant extracts aimed at supporting natural testosterone levels, energy, and performance.
While results can be subtle, combining these ingredients may support hormone balance, stress response, and sexual vitality over time.
Supplements work best when paired with healthy habits. Here are key lifestyle tips to naturally enhance stamina and performance:
Making these changes alongside supplement use can maximize results.
How long before I might notice effects?
Are these supplements safe if I take blood pressure or hormone meds?
Always consult your healthcare provider. Some ingredients may interact with medications or affect blood pressure.
Can women benefit too?
Yes. Nitric oxide ingredients like L-citrulline and L-arginine may enhance blood flow and arousal in women. Testosterone-focused blends are designed for men.
Will combining both supplements provide extra benefit?
Possibly. Combining NO boosters with testosterone support may enhance energy and performance, but check dosages and interactions before stacking.
When it comes to boosting bedroom stamina and performance, nitric oxide and testosterone supplements offer promising support.
These supplements aren’t magic bullets. They work best when paired with quality sleep, regular exercise, a nutrient-dense diet, and stress management. Used thoughtfully, they can help you feel more confident, energized, and connected in your intimate life.
You deserve to feel your best. And with the right tools and information, you're already one step closer.
Mark Goldberg, LCMFT, CST, is a certified sex therapist and founder of the Erectile Dysfunction Radio Podcast and eiqmen.com, resources that educate and empower men to overcome sexual dysfunction, build confidence, and enhance relationship satisfaction. He provides therapy to help individuals better understand and express their emotions, manage depression and anxiety, and improve their relationships. Through his practice, the Center for Intimacy, Connection, and Change, Mark is passionate about helping couples navigate challenges and create meaningful, lasting change.
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