Mate Endurance is an all-natural supplement designed to treat PE. Its ingredients are meant to lightly mimic the ejaculation-delaying effect of certain antidepressants, but without the side effects of those stronger medications.
It does this primarily through the inclusion of L-Tryptophan, which may affect serotonin levels in a similar way to SSRI antidepressants, but on a much smaller scale.
As the founder of Mate noted, antidepressants can often cause delayed ejaculation. He imagined copying those effects just enough to reduce PE without excessively delaying orgasm or negatively interfering with sex or mental health.
The current price of a one-month supply is $43, with free shipping included. The daily dosage of Mate Endurance is 2 pills, at once, once a day.
The company also funded its own small-scale clinical study to view the effectiveness of their product on men. In the trial, half the participants took the supplement in the evening, and the other half took a placebo.
According to Mate’s study, they found that:
68% had an increase in sexual satisfaction
66% felt an increase over their timing
70% had a decrease in sexual stress and anxiety
While these are interesting results, it’s worth noting that the participants were told not to time their sexual encounters, which is often an important measure during clinical trials for curing premature ejaculation.
Instead, they were simply told to report their feelings on the matter, along with their overall satisfaction.
Now, let's dive further into the research on the ingredients themselves to see if they’re beneficial against PE.
Mate Endurance Ingredients
Mate Endurance has 12 ingredients, including:
Grape Seed Extract
Niacin (vitamin B3)
While these ingredients are generally safe for most healthy adults, there are few studies on them directly related to premature ejaculation.
However, in a 2016 clinical trial, they found that a combination of four ingredients helped to significantly increase sexual longevity for men affected by PE.
Two of the ingredients in the study, L-Tryptophan and Tribulus, are also present in Mate Endurance. The other two ingredients, Satureja Montana and Phyllanthus Emblica, are not in Mate Endurance.
Since the ingredients and dosages aren't identical, we can't say for certain that Mate's combination will be equally as effective as in the study.
However, it does show that there is potentially some promise in some of the ingredients, although it's not conclusive.
Many of the other ingredients on the list are included to help increase nitric oxide production to aid in firmer erections, according to the company website.
How to Take Mate Endurance
The Mate Endurance dosage is two pills at once, once a day. During the company’s own trial, they had participants take the pills at night on an empty stomach.
The company doesn’t make a recommendation on when to take Mate, or whether it’s best with food or not. It may be ideal to follow their own trial and take it at night on an empty stomach.
When Do You See Results
According to the company, some users may experience benefits from Mate Endurance within the first few weeks of taking the supplement daily.
However, they also add that it may take up to three months to experience the full benefits.
This is a common trend among herbal sexual enhancement supplements, as it may take time for the ingredients to begin causing noticeable and beneficial changes.
According to user reviews, this timeline seems fairly accurate as well.
Mate Endurance Side Effects
Based on the clinical study conducted by Mate Endurance, some users experienced the following side effects:
It’s important to consult with your doctor before trying Mate Endurance or any other sexual health supplement.
Some conditions that may potentially interfere with the product include:
High blood pressure
Any other chronic conditions
Mate Endurance Reviews
Currently, there are few non-sponsored official reviews available of Mate Endurance.
While the company did sponsor its own clinical trial, the sample size was quite small and they did not ask users to time themselves during intercourse, which would have provided more clear data about Mate Endurance’s effectiveness.
However, the company currently has 33 verified reviews on their website, and the average rating is 5-stars.
The common trend in these 5-star reviews is that:
The product works within two weeks to three months
It can help to last longer in bed
It allows for greater control over ejaculation
It helps to minimize the effects of PE while taking the supplement
For some users who gave 3-star or 4-star reviews, they claimed that the product either didn’t work or did not provide enough benefit to justify the price.
As of now, there are no 2-star or 1-star reviews, and there are no claims of side effects that stand out as dangerous or concerning.
The ingredients in Mate Endurance show some potential for alleviating PE symptoms. Further studies will be needed to see how effective they are for most men.
The available studies are either from the company directly, or feature other ingredients, making the results inconclusive.
While the product may be safe and potentially effective, it can also take a long time to begin working.
Those who want a quicker solution may opt for products like a lidocaine-based desensitizing spray. It can begin working immediately to treat PE and help men last longer.
Our team has over a decade of experience in the sexual wellness field and are experts in sexual dysfunctions, like premature ejaculation. We help couples and individuals better understand treatment options available for different types of sexual needs and educate the public on all things related to intimacy. All of our authored content is medically reviewed for accuracy and reliability.
Absorption Pharmaceuticals LLC (Promescent) has strict informational citing guidelines and relies on peer-reviewed studies, academic or research institutions, medical associations, and medical experts. We attempt to use primary sources and refrain from using tertiary references and only citing trustworthy sources. Each article is reviewed, written, and updated by Medical Professionals or authoritative Experts in a specific, related field of practice. You can find out more about how we ensure our content is accurate and current by reading our editorial policy.
Richard DM, Dawes MA, Mathias CW, Acheson A, Hill-Kapturczak N, Dougherty DM. L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications. Int J Tryptophan Res. 2009 Mar 23;2:45-60. doi: 10.4137/ijtr.s2129. PMID: 20651948; PMCID: PMC2908021. Accessed on Mar, 14, 2023.
Higgins A, Nash M, Lynch AM. Antidepressant-associated sexual dysfunction: impact, effects, and treatment. Drug Healthc Patient Saf. 2010;2:141-50. doi: 10.2147/DHPS.S7634. Epub 2010 Sep 9. PMID: 21701626; PMCID: PMC3108697. Accessed on Mar, 14, 2023.
"A Double-Blind, Placebo-Controlled Study of the Effectiveness of Mate Endurance TM Dietary Supplement on Sexual Satisfaction, Ejaculatory Control, and Distress in Men with Premature Ejaculation - Open Journal of Urology." Cdn.shopify.com, 2020, cdn.shopify.com/s/files/1/0383/8918/6700/files/Open_Journal_of_Urology_mate_endurance_Premature_Ejaculation_Clinical_Study.pdf
Sansalone S, Russo GI, Mondaini N, Cantiello F, Antonini G, Cai T. A combination of tryptophan, Satureja montana, Tribulus terrestris, Phyllanthus emblica extracts is able to improve sexual quality of life in patient with premature ejaculation. Arch Ital Urol Androl. 2016 Oct 5;88(3):171-176. doi: 10.4081/aiua.2016.3.171. PMID: 27711088. Accessed on Mar, 14, 2023.
Singh S, Nair V, Gupta YK. Evaluation of the aphrodisiac activity of Tribulus terrestris Linn. in sexually sluggish male albino rats. J Pharmacol Pharmacother. 2012 Jan;3(1):43-7. doi: 10.4103/0976-500X.92512. PMID: 22368416; PMCID: PMC3284036. Accessed on Mar, 14, 2023.
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