8 Best Supplements & Vitamins For Premature Ejaculation

Supplements and vitamins can potentially be an effective treatment option for premature ejaculation. Learn the best ones to take to last longer in bed.

The Promescent Team
Hands on, practical experience – this is our expertise
by The Promescent Team Last updated 12/18/2023
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vitamins and supplements for premature ejaculation

Premature ejaculation (PE) happens when a man climaxes too fast without any control of the orgasm.

And while it sometimes comes with embarrassment and frustration, PE is a common sexual dysfunction.

Quick FAQs

Some supplements that may help with treating premature ejaculation include zinc, chinese herbal medicines, and magnesium.

Vitamins that may help with treating premature ejaculation include Vitamin D, Vitamin B12, and Folic Acid.

Other effective treatments for premature ejaculation include lidocaine spray, benzocaine wipes, and pelvic floor exercises.

Research shows that upwards of 30% of all men experience premature ejaculation at some point in their life. Most men find that they can treat the symptoms of PE with lifestyle changes, techniques that delay ejaculation, and supplements.

Let's take a closer look at the best supplements for premature ejaculation and find the right premature ejaculation treatment for you.

Supplements for Premature Ejaculation

Supplements containing vitamins and minerals boost numerous bodily functions, including sexual health.

Some over-the-counter (OTC) supplements can address the causes of your premature ejaculation and alleviate the symptoms.

Always consult with your personal physician before starting any vitamin, mineral, or supplement.

1. Zinc

Zinc supplements are often taken for reproductive health, immunity, metabolism, and cell growth.

But some studies discovered that zinc boosts production of testosterone, which may address premature ejaculation related to low testosterone.

Pro Tip: Learn more about Zinc and testosterone and find out how it can help you. 

Zinc may also have a vital role in prostate and ejaculatory health and support sperm release and motility.

Be mindful that taking too much can lead to zinc poisoning or a zinc overdose. Be sure to follow dosage recommendations.

2. Chinese herbal medicines

One study shows that traditional Chinese medicines (TCM) help some men who experience premature ejaculation due to kidney disease.

The study shows that TCM can improve blood flow, increase sex drive, and balance the body's systems.

Chinese herbal medications are sometimes more effective when used in combination with another treatment.

For example, one study highlighted the use of traditional Chinese medicine in combination with selective serotonin reuptake inhibitors (SSRIs). The results show that combining SSRIs and TCM may increase ejaculation time by up to two minutes.

3. Magnesium

Science has found a correlation between premature ejaculation and low magnesium. The association is due to the fact that magnesium may play a role in the transport of semen.

One way to ensure you're getting enough of the mineral is to introduce a magnesium-rich diet to your day-to-day life.

  • pumpkin seeds
  • almonds
  • spinach
  • peanuts
  • shredded wheat cereal
  • black beans
  • whole wheat bread
  • peanut butter
  • oatmeal
  • dark chocolate
  • and more

Some men find that they can't obtain enough magnesium through food alone.

Pro Tip: Did you know certain foods can contribute to PE? Find out if changing your diet can fix PE.

OTC supplements are available that contain a safe amount of magnesium to address premature ejaculation symptoms.

4. Ginseng

Ginseng is a traditional Chinese medicine that's used in health supplements to support many of the body's symptoms.

  • boosts immunity response and disease resistance
  • stimulates nervous system
  • promotes central nervous system functions
  • regulates blood sugar
  • increases energy
  • improves brain function
  • reduces cancer risks

One clinical study showed that men who took ginseng supplements experienced harder erections, higher libido, and better sexual satisfaction.

Ginseng may help lower blood sugar and regular glucose metabolism, which can improve overall health and address causes of premature ejaculation.

Evidence on the effectiveness of ginseng when treating PE is limited and requires more scientific research.

Pro Tip: Promescent make a safe and effective nitric oxide boosting supplement called VitaFLUX that can help treat premature ejaculation.

Vitamins for Premature Ejaculation

Research is ongoing on the effects of vitamins and minerals when treating premature ejaculation.

However, plenty of studies show a link between vitamin and mineral deficiencies and PE.

1. Vitamin D

A vitamin D deficiency can lead to fatigue, hair loss, and depression. Low vitamin D levels are also associated with premature ejaculation, and vitamin D can affect testosterone levels in men.

Research also shows that vitamin D supports serotonin production, which regulates mood, sleep, and sexual behavior.

Your doctor may recommend supplementing vitamin D for premature ejaculation if you're unable to get enough through sunlight or diet.

2. Vitamin B12

Vitamin B12 is vital for red blood cell production and nerve function and is one of the best vitamins for premature ejaculation.

One study showed that some men who struggled with premature ejaculation had lower levels of Vitamin B12 than those with normal levels.

Another study provided further evidence that B12 deficiency can lead to a higher risk of PE.

Vegans and vegetarians often have trouble getting enough B12 through their diet and require supplements.

3. Folic Acid

Our bodies use folic acid, which is the natural form of Vitamin B9, to create blood cells and repair damaged DNA and genetic material.

Administering folic acid can help address symptoms of premature ejaculation by helping to boost serotonin levels.

One meta-analysis shows low folic acid may be an independent factor for developing PE.

Folic acid, in combination with tadalafil (Cialis), had a positive effect when treating rapid climax in men.

4. Biotin

Biotin, also known as vitamin B7, primarily helps the body to convert food into energy. But it’s also been found to potentially help with PE as well.

One study found that Biotin contributes to normal psychological and sexual function, which researchers believe is useful to the management of patients with PE.

Other Treatments for Premature Ejaculation

Other treatment options are available if supplements and vitamins aren't quite enough to address the symptoms of PE. Here are a few of the best ones to consider:

1. Lidocaine Spray

Over-the-counter lidocaine spray, such as Promescent Desensitizing Spray, helps with treating PE by reducing the sensation in the penis and delaying orgasm.

Lidocaine is a topical anesthetic that blocks the signals at the nerve endings in the skin. Desensitizing spray should be applied to the penis 10 to 15 minutes before sexual activity.

A study found that when using Promescent Delay Spray, average ejaculation latency time was 11.16 minutes, compared to 6.81 minutes when the product was not used.

2. Benzocaine Wipes

Premature ejaculation wipes contain benzocaine that blocks sodium channels that causes penis sensation.

A small study on the effectiveness of benzocaine wipes found that participants experienced few PE symptoms over a 2-month period.

3. Topical creams

OTC topical anesthetic creams and gels contain the same numbing agent as wipes and sprays that help delay ejaculation.

One study found topical anesthetic creams increase the time it takes to climax, but more conclusive research is needed.

4. Pelvic Floor Exercises

Research has found that pelvic floor or kegel exercises can be effective in men who struggle with PE.

At the conclusion of a study where 40 men were treated with 12-week pelvic floor muscle rehabilitation, 82.5% were able to gain control of their ejaculatory reflex.

Patients examined after six months increased their ejaculation time from 39.8 seconds to 112.6 seconds on average.

5. Edging

The stop-start technique, or edging, is a method of delaying orgasm by drawing out sexual pleasure.

The moment you feel the urge to ejaculate, stop sexual activity immediately. As soon as you feel the arousal decrease, resume sexual activity.

Repeat the edging process as much as necessary to manage premature ejaculation. Research concluded that this method can be partially effective in treating PE.

6. Masturbation before sex

Many people believe masturbating before sex helps you last longer when intercourse does happen.

It has also been found to be partially effective in treating PE, but more scientific research is needed.

7. Thickened condoms

In one study, thickened condoms were found to significantly prolong the time to ejaculate in the premature ejaculation group. 

Penile erection time was also prolonged in those men using premature ejaculation condoms compared to those using ordinary condoms.

8. Medication

A study found that Serotonin Reuptake Inhibitors (SSRIs) improved premature ejaculation symptoms compared to the placebo.

Researchers conclude that SSRIs boost happiness and give men more control over their orgasms.

Your doctor may prescribe an SSRI for premature ejaculation. It typically takes one to two weeks to start seeing the effects of SSRIs. Some of the more common ones used are:

9. Therapy

Sometimes, premature ejaculation is due to psychological reasons. In those cases, supplements and delay techniques may not be enough.

Cognitive behavioral therapy (CBT) and sex therapy are proven ways to find the root cause of PE. CBT can also relieve stress, anxiety, and depression, which can all cause sexual dysfunction.

Couples who struggle with premature ejaculation may also benefit from couples sex therapy, as they're able to discuss sex openly in a safe space.

Premature Ejaculation Symptoms

Some men may experience premature ejaculation once or twice. When PE happens infrequently, there is not much to worry about.

However, contact your physician or a urologist if you experience certain premature ejaculation symptoms.

  • Climax happens within one minute of penetration three out of four times you have sex, and it causes you distress.
  • Premature ejaculation has happened for six months or longer, causing anxiety that's affecting everyday life.
  • You can't find an external cause such as stress, medication side effects, or lifestyle.

Possible causes for premature ejaculation

Physical and psychological issues can lead to the occurrence of premature ejaculation.

One of the biggest causes of PE is the actual fear of orgasming too soon. You may find that slowing down and not hurrying through sex may prevent rapid climax.

Other psychological causes of premature ejaculation include:

  • depression or anxiety
  • sexual abuse or traumatic experience with sex
  • stress
  • relationship issues

Physical causes for PE can include:

  • low testosterone
  • prostate problems
  • thyroid problems


A lot of men experience premature ejaculation during their lifetime. It can happen once or twice or develop into a long-term sexual dysfunction.

The good news is that PE is usually treatable. Supplements specifically may address the vitamin and mineral deficiencies that lead to premature ejaculation.

But sometimes supplementing vitamins and minerals isn't enough to alleviate the symptoms of PE.

Lidocaine spray and benzocaine wipes can help to reduce penis sensitivity, allowing men to last longer in the bedroom.

If premature ejaculation becomes frequent or causes distress, let your doctor know so they can help you find the right treatment.

The Promescent Team

The Promescent Team

Our team has over a decade of experience in the sexual wellness field and are experts in sexual dysfunctions, like premature ejaculation. We help couples and individuals better understand treatment options available for different types of sexual needs and educate the public on all things related to intimacy. All of our authored content is medically reviewed for accuracy and reliability.


Absorption Pharmaceuticals LLC (Promescent) has strict informational citing guidelines and relies on peer-reviewed studies, academic or research institutions, medical associations, and medical experts. We attempt to use primary sources and refrain from using tertiary references and only citing trustworthy sources. Each article is reviewed, written, and updated by Medical Professionals or authoritative Experts in a specific, related field of practice. You can find out more about how we ensure our content is accurate and current by reading our editorial policy.

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The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition.

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